CD39 抗体
Quick Overview for CD39 抗体 (ABIN7113721)
抗原
See all CD39 (ENTPD1) 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- ENTPD1 antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- ectonucleoside triphosphate diphosphohydrolase 1
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亚型
- IgG
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应用备注
- WB: 1:500-1:2000, IP: 1:200-1:1000, IHC: 1:20-1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- CD39 (ENTPD1) (Ectonucleoside Triphosphate diphosphohydrolase 1 (ENTPD1))
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别名
- ENTPD1
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背景
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Synonyms: Ectonucleoside triphosphate diphosphohydrolase 1|ATP diphosphohydrolase (ATP-DPH, ATPDase)|Ecto-ATP diphosphohydrolase 1 (Ecto-ATPDase 1, Ecto-ATPase 1)|Ecto-apyrase|Lymphoid cell activation antigen|Nucleoside triphosphate diphosphohydrolase 1 (NTPDase1)|ENTPD1|CD39
Background: ENTPD1(Ectonucleoside triphosphate diphosphohydrolase 1) is also named as CD39, NTPDase 1, Ecto-ATPDase 1 and belongs to the GDA1/CD39 NTPase family. In the nervous system, it can hydrolyze ATP and other nucleotides to regulate purinergic neurotransmission.It is a noncovalent tetrameric protein and that detergent inhibition of enzymatic activity is caused by dissociation of ectoapyrase tetramers into monomers(PMID: 9733785).And it is a 70-to 100- kDa protein that is heavily N-glycosylated(PMID:7930580). It has 3 isoforms produced by alternative splicing. CD39 preferentially occurred as a dimer that could be dissociated into monomeric forms.(PMID: 12694193). The soluble isoform of CD39(38-478 amino acid) locates to the extracellular part and FNab01474 recognizes both the 3 isoforms and soluble form of CD39(38-478aa) molecule.
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分子量
- 75-95 kDa
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UniProt
- P49961
抗原
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